Sharaxaada

Sugammadex sodium waa derivative γ-cyclodextrin synthetic, oo u dhaqmo sidii wakiilka rogaal celis cusub block neuromuscular.

Magaca guud: summadex (soo GAM ma dex)
Magaca Brand: Bridion

Sugammadex waxay beddeshaa saameynta daawooyinka qaarkood ee la bixiyo inta lagu jiro hababka qalliinka si loo nasiyo muruqyadaada.

Sugammadex waxa loo isticmaalaa dhamaadka qalliinka, si ay gacan uga geysato dib u soo celinta shaqadii muruqa ee xannibay muddada qaliinka ee daawooyinka kale.

Sugammadex waxa kale oo loo isticmaali karaa ujeedooyin aan lagu xusin hagaha daawaynta.

Waxa loo isticmaalaa in lagu beddelo saamaynta daawooyinka qaarkood.

Gudaha Vivo

Duritaanka summadex wax saameyn ah kuma laha cadaadiska dhiigga ama garaaca wadnaha.Kadib duritaanka qiyaasta rocuronium ee sare, soo kabashada 90% ee saamiga tareenka-afarta waxay qaadataa 28 min (SD 7 min) milix ka dib, 26 min (SD 9.5 min) kadib 1 mg/kg sugammadex, iyo 8 min (SD 3.6 min) kadib 2.5 mg/kg summadex [1].Sugammadex waxay sababtaa dib u noqosho degdeg ah oo dhammaystiran oo rocuronium-ku-abuuray neuromuscular block.Waqtiga soo kabashada ee tababbarka afar saamiga = 0.9 ka dib soo kabashada lama filaanka ah waa 14.4 min (SD=3.4 min; n=14).Tan waxaa si weyn hoos loogu dhigay 3.7 min (SD=3.3 min; n=4) oo leh summadex 0.5 mg/kg iyo 1.9 min (SD=1.0 min; n=4) oo leh summadex 1.0 mg/kg[2].Qiyaasta nolosha nuska ah ee summadex ee daanyeerka Rhesus waa 30 (SEM=4.9) min [3].

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