Vericiguat waa apyrazolopyridinetaasi waa5-fluoro-1H-pyrazolo[3,4-b]pyridinekaas oo amino hydrogen ee booska 1 lagu bedelay koox 2-fluorobenzyl ah iyohydrogenbooska 3 waxaa bedelay 4,6-diamino-5-[(methoxycarbonyl)amino] pyrimidin-2-yl group. Waa mid milmaguanylatekicinta cyclase kaas oo loo isticmaalo daawaynta wadne xanuunka daba dheeraada. Waxay leedahay door ah mid lagu milmayoguanylatecyclase activator, wakiilka vasodilator iyo wakiilka antihypertensive. Waa anaminopyrimidine, apyrazolopyridine, carbamate ester iyo iskudhis organofluorine ah.

Vericiguat waxa uu ku socdaa baadhitaan tijaabo caafimaad NCT02861534 (Daraasad lagu sameeyay Vericiguat ee ka qaybgalayaasha leh Wadnaha Failure iyadoo la dhimay jajabka Ejection (HFrEF) (MK-1242-001)).

Vericiguat waa mid la xallin karoGuanylateKicinta wareegga. Habka ficilka ee vericiguat waa sida aGuanylateKicinta wareegga.

Vericiguat waa daawo loo isticmaalo in lagu maareeyo laguna daweeyo wadne-gabowga iyada oo leh jajab-saarid la dhimay (HFrEF). Waxay faa'iido u leedahay wadne-gabka joogtada ah ee ka sii daraya, wadne-gabka wadnaha ee dhawaan decompensated. Vericiguat ma dheereyso badbaadada laakiin waxay ka hortagtaa isbitaal dhigista. Hawshani waxay qeexaysaa tilmaamaha, habka ficilka, qiyaasta, iyo qaabka maamulka ee kooxda xirfadlayaasha ah, saamaynta xun, iska-hor-imaadyada, iyo dhowr tijaabo oo lagu taageerayo caddaynta waxtarka daawada ee HFrEF.