Calcium Rosuvastatin
| 瑞舒伐他汀钙 | Calcium Rosuvastatin | 147098-20-2 | Guriga dhexdiisa/CEP |
| RSM (Crystal) | 147118-40-9 | Guriga dhexdiisa | |
| RSM (Ceyriin) | 147118-40-9 | Guriga dhexdiisa | |
| RSP | - | Guriga dhexdiisa | |
| RS-8 | 147118-36-3 | Guriga dhexdiisa | |
| RS-8-1 | 147118-37-4 | Guriga dhexdiisa | |
| TP-8 | 131466-61-0 | Guriga dhexdiisa | |
| TP-11 | 147118-35-2 | Guriga dhexdiisa | |
| TP-13 | 147118-39-6 | Guriga dhexdiisa | |
| RS-10 | 289042-12-2 | Guriga dhexdiisa | |
| RS-11 | 355806-00-7 | Guriga dhexdiisa |
Sharaxaada
Rosuvastatin Calcium (BANM, JAN, USAN) waxaa loo yaqaanaa Rosuvastatin gudaha Mareykanka.iyo HMG-CoA reductase inhibitor oo tartan leh oo leh IC50 ee 11 nM[1].Calcium Rosuvastatin waxay si xoog leh u xannibaysaa hidda-wadaha ether-a-go-go ee bini'aadamka (hERG) hadda leh IC50 ee 195 nM, dib-u-soo-celinta wadnaha oo dib-u-dhac ku yimaada, oo markaa ficil-celinta muddada dheer ee suurtagalka ah (APDs) iyo hagaajinta muddada QT (QTc) [2].Calcium Rosuvastatin waxay yaraynaysaa muujinta hERG-ga bislaaday iyo is dhexgalka borotiinka shoogga kulaylka 70 (Hsp70) iyo borotiinka hERG.Calcium Rosuvastatin waxay aad waxtar ugu leedahay hoos u dhigista lipoprotein cufan (LDL), kolestaroolka, triglycerides, iyo heerarka borotiinka C-reactive[3].
Macluumaad dheeraad ah oo ku saabsan heshiisyada magacaabista daroogada: Magacyada Caalamiga ah ee aan hantida lahayn.
Ogeysiis Muhiim ah: Xogta caalamiga ah ee Drugs.com waxay ku jirtaa sii deynta BETA.Tani waxay la macno tahay inay weli ku socoto horumar waxaana laga yaabaa inay ku jiraan waxyaabo aan sax ahayn.Looguma talagalin in lagu badalo khibrada iyo xukunka dhakhtarkaaga, farmashiistaha ama xirfadlaha kale ee daryeelka caafimaadka.Waa inaan loo fasirin inay muujinayso in isticmaalka dawo kasta ee waddan kasta ay badbaado, ku habboon tahay ama waxtar kuu leedahay.La tasho xirfadlahaaga daryeelka caafimaadka ka hor intaadan qaadan wax daawo ah.
Gudaha Maraykanka, Rosuvastatin (Rosuvastatin systemic) waa xubin ka tirsan fasalka dawada ee statins waxaana loo isticmaalaa in lagu daweeyo Atherosclerosis, Cholesterol Sare, Cholesterol Sare - Qoyska Heterozygous, Cholesterol Sare - Homozygous Qoyska, Hyperlipoproteinemia, Hyperlipoproteinemia Nooca IIa - Kor u kaca LDL, Nooca IIa IIb - Kor u kaca LDL VLDL, Hyperlipoproteinemia Nooca III - Kor u kaca beta-VLDL IDL, Hyperlipoproteinemia Nooca IV - VLDL oo sarreeya, Hypertriglyceridemia iyo Kahortagga Cudurrada Wadnaha.
Asalkii hore
Xakamaynta doorashada, tartanka leh ee HMG-CoA reductase, kaas oo sidoo kale ah antilipemic.
Kaydinta
| Budada | -20°C | 3 sano |
| 4°C | 2 sano | |
| Ku milmay | -80°C | 6 bilood |
| -20°C | 1 bil |
Qaab dhismeedka kiimikada
Soo jeedin18Mashaariicda Qiimaynta Joogtada Tayada ee la ansixiyay4iyo6mashaariicda ayaa ku socda ansixinta.
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Kormeerka tayada wuxuu ku socdaa dhammaan wareegga nolosha ee alaabta si loo hubiyo tayada iyo saameynta daaweynta.
Kooxda Arrimaha Sharciyaynta Xirfadlayaasha waxay taageertaa shuruudaha tayada inta lagu jiro codsiga iyo diiwaangelinta.
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