Captopril
Sharaxaada
Captopril (SQ-14534) waa horjooge awood leh, tartan u leh angiotensin-converting enzyme (ACE).
In Vitro
Captopril (SQ-14534) ayaa la muujiyay in ay leedahay faa'iidooyin jirro iyo dhimasho la mid ah kuwa diuretics iyo beta-blockers ee bukaannada hypertensive.Captopril (SQ-14534) ayaa lagu muujiyay inay dib u dhigayso horumarka nephropathy macaanka, iyo enalapril iyo lisinopril waxay ka hortagayaan horumarinta nephropathy bukaanada normoalbuminuric ee qaba cudurka macaanka[1].Saamiga siman ee cis iyo dowladaha trans ee Captopril (SQ-14534) ayaa ku jira xalka iyo in ensaymku uu doorto kaliya gobolka trans ee xannibaadaha oo soo bandhigaya dhamaystirka qaabdhismeedka iyo isteeroogga elektaroonigga ah iyada oo ay weheliso jeexdin substrate ah [2].
MCE si madaxbanaan uma xaqiijin saxnaanta hababkan.Waxay yihiin tixraac kaliya.
Tijaabo Caafimaad
| Lambarka NCT | Kafiil | Xaalad | Taariikhda billowga | Marxaladda |
| NCT03179163 | Jaamacadda Penn State | Machadka Qaranka ee Wadnaha, Sambabka, iyo Dhiiga (NHLBI) | Dhiig karka, lama huraan ah | July 20, 2016 | Wajiga 1|Wejiga 2aad |
| NCT03660293 | Jaamacadda Tanta | Sonkorowga Mellitus, Nooca 1 | Abriil 1, 2017 | Ma khuseyso |
| NCT03147092 | Centro Neurológico de Pesquisa e Reabiitação, Brazil | Dhiigkarka | Dhiig karka | Febraayo 1, 2018 | Wajiga hore 1 |
| NCT00252317 | Rigshospitalet, Denmark | Aortic Stenosis | November 2005 | Wajiga 4 |
| NCT02217852 | Isbitaalka Galbeedka Shiinaha | Dhiig-karka | Ogosto 2014 | Wajiga 4 |
| NCT01626469 | Brigham iyo Isbitaalka Haweenka | Nooca 2aad ee Sonkorowga Mellitus | May 2012 | Wajiga 1|Wejiga 2aad |
| NCT00391846 | AstraZeneca | Wadnaha oo Fashilmay | Oktoobar 2006 | Wajiga 4 |
| NCT00240656 | Hebei Medical University | Dhiig-karka, sambabada | Oktoobar 2005 | Wajiga 1 |
| NCT00086723 | Jaamacadda Waqooyi-galbeed | Machadka Qaranka ee Kansarka (NCI) | Burada adag ee qaangaarka ah ee aan la cayimin, qaaska ah borotokoolka | July 2003 | Wajiga 1|Wejiga 2aad |
| NCT00663949 | Jaamacadda Shiraz ee culuumta caafimaadka | Cudurka macaanka ee nephropathy | Febraayo 2006 | Wajiga 2|Wejiga 3aad |
| NCT01437371 | Isbitaalka Jaamacadda, Clermont-Ferrand| Adeege|LivaNova | Wadnaha oo Fashilmay | Ogosto 2011 | Wajiga 3 |
| NCT04288700 | Jaamacadda Ain Shams | Hemangioma dhallaanka | Oktoobar 1, 2019 | Wajiga 4 |
| NCT00223717 | Jaamacadda Vanderbilt | Xarunta Caafimaadka ee Jaamacadda Vanderbilt | Dhiig-karka | Janaayo 2001 | Wajiga 1 |
| NCT02770378 | Jaamacadda Ulm|Daawaynta Kansarka la isku halayn karo | Glioblastoma | November 2016 | Wajiga 1|Wejiga 2aad |
| NCT01761916 | Instituto Materno Infantil Prof. Fernando Figueira | Preeclampsia | Janaayo 2013 | Wajiga 4 |
| NCT01545479 | Instituto de Cardiologia ee Rio Grande do Sul | Cudurka kelyaha | Janaayo 2010 | Wajiga 4 |
| NCT00935805 | Hospital de Clinicas de Porto Alegre|Conselho Nacional de Desenvolvimento Científico e Tecnológico|Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil | Sonkorowga Mellitus|Heerka Dhiig karka | July 2006 |
|
| NCT00742040 | Cisbitaalka Caruurta Xanuunsan | Cudurka Wadnaha | Ogosto 2008 | Wajiga 2 |
| NCT03613506 | Jaamacadda Wuhan | Saamaynta dhinaca shucaaca | Qaadashada Captopril | Oktoobar 25, 2018 | Wajiga 2 |
| NCT00004230 | Jaamacadda Waqooyi-galbeed | Machadka Qaranka ee Kansarka (NCI) | Kansarka | Oktoobar 1999kii | Wajiga 3 |
| NCT00660309 | Novartis | Nooca 2aad ee Sonkorowga Mellitus | Abriil 2008 | Wajiga 4 |
| NCT00292162 | NHS Greater Glasgow iyo Clyde | Wadnaha oo daba dheeraada | Janaayo 2007 | Ma khuseyso |
| NCT01271478 | Coordinación de Investigación en Salud, Mexico | Caabuqa|Cudurka Kelyaha ee heer-dhamaadka | Ogosto 2009 | Wajiga 4 |
| NCT04193137 | Jaamacadda Caafimaadka ee Chongqing | Aldosteronism aasaasiga ah | November 30, 2019 |
|
| NCT00155064 | Isbitaalka Jaamacadda Qaranka ee Taiwan | Hyperaldosteronism | July 2002 | Wajiga 4 |
| NCT01292694 | Jaamacadda Vanderbilt | Xarunta Caafimaadka ee Jaamacadda Vanderbilt | Dhiig-karka | Maarso 2011 | Wajiga 1 |
| NCT00917345 | Isbitaalka Jaamacadda Qaranka ee Taiwan | Novartis | Aldosteronism aasaasiga ah | Janaayo 2008 |
|
| NCT00077064 | Kooxda Daaweynta Shucaaca Oncology | Machadka Qaranka ee Kansarka (NCI)|NRG Oncology | Kansarka Sambabada|Dhibaatada Sambabada | Shucaaca Fibrosis | Juun 2003 | Wajiga 2 |
Kaydinta
| Budada | -20°C | 3 sano |
| 4°C | 2 sano | |
| Ku milmay | -80°C | 6 bilood |
| -20°C | 1 bil |
Qaab dhismeedka kiimikada
Soo jeedin18Mashaariicda Qiimaynta Joogtada Tayada ee la ansixiyay4iyo6mashaariicda ayaa ku socda ansixinta.
Nidaamka maaraynta tayada sare ee caalamiga ah ayaa dhigay aasaas adag oo iib ah.
Kormeerka tayada wuxuu ku socdaa dhammaan wareegga nolosha ee alaabta si loo hubiyo tayada iyo saameynta daaweynta.
Kooxda Arrimaha Sharciyaynta Xirfadlayaasha waxay taageertaa shuruudaha tayada inta lagu jiro codsiga iyo diiwaangelinta.
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