Baloxavir Marboxil 1985606-14-1
Asalkii hore
Baloxavir marboxil waa daawada fayraska ka hortagta waana daawada endonuclease inhibitor. Jiirka iyo daanyeerka, xoogga saarista daawadu waxay ka hoosaysaa inta ugu yar ee lagu ogaanayo hal maamul oo afka ah oo daawada ah. Qaababka caabuqa ee hargabka A iyo B (oo ay ku jiraan noocyada u adkaysta daawooyinka fayraska ee jira), Baloxavir marboxil waxay leedahay saameyn gaar ah.
Guryaha Kiimikada
| Kaydinta | Ku kaydi heerkulka -20°C |
| M.Wt | 571.55 |
| Cas No. | 1985606-14-1 |
| Formula | C27H23F2N3O7S |
| La mid ah | S-033188 |
| Solubility | Ku milmay DMSO |
| Magaca Kiimikada | ((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H-[1,4] oxazino [3,4-c] pyrido [2,1-f] [1,2,4]triazin-7-yl) oxy) methyl methyl carbonate |
| SDF | Soo deji SDF |
| Dhoola-cadaynta Canonical | O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O |
| Xaalada Maraakiibta | Xalka muunadda qiimaynta: markab leh baraf buluug ah. Dhammaan cabbirrada kale ee la heli karo: markabka RT, ama baraf buluug ah marka la codsado. |
| Talooyin guud | Si aad u hesho milmayn sare, fadlan ku diiri tuubada 37°C oo ku rux qubeyska ultrasonic in muddo ah. Xalka kaydka waxa lagu kaydin karaa hoos -20°C dhowr bilood. |
Qaab dhismeedka kiimikada
Soo jeedin18Mashaariicda Qiimaynta Joogtada Tayada ee la ansixiyay4iyo6mashaariicda ayaa ku socda ansixinta.
Nidaamka maaraynta tayada sare ee caalamiga ah ayaa aasaas adag u dhigay iibka.
Kormeerka tayada wuxuu ku socdaa dhammaan wareegga nolosha ee alaabta si loo hubiyo tayada iyo saameynta daaweynta.
Kooxda Arrimaha Xeer-ilaalinta Xirfadlayaasha waxay taageertaa shuruudaha tayada inta lagu jiro codsiga iyo diiwaangelinta.
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