Soosaarayaasha iyo alaab-qeybiyeyaasha China Chlorothiazide |CPF

Chlorothiazide

Sharaxaad Gaaban:

Magaca API	Tilmaam	Tilmaamid	US DMF	Midowga Yurub DMF	CEP
Chlorothiazide	Diuretics	USP/EP

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Asalkii hore

Chlorothiazide waa horjooge anhydrase kaarboon ah oo xoogaa ka awood yar acetazolamide.Xaruntan ayaa la muujiyey inay xannibto dib-u-noqoshada soodhiyamka iyo ion chloride.

Sharaxaada

Chlorothiazide waa duriye iyo ka hortag dhiig-karka.(IC50=3.8 mM) Bartilmaameedka: Kuwo kale Chlorothiazide sodium (Diuril) waa durayo loo isticmaalo gudaha goobta isbitaalka ama si shakhsi ah loogu isticmaalo si loo maareeyo dareeraha xad-dhaafka ah ee la xiriira wadno-qabsiga wadnaha.Waxa kale oo loo isticmaalaa sidii antihypertensive.Inta badan waxa loo qaataa qaab kaniini ah, inta badan waxa afka laga qaataa hal ama laba jeer maalintii.Goobta ICU, chlorothiazide ayaa la siiyaa si ay u walaaqdo bukaanka marka lagu daro furosemide (Lasix).Ku shaqaynta hab ka duwan furosemide, oo si buuxda u nuugo sida ka joojinta dib loo habeeyay ee lagu maamulo tuubada sanka (tuubada NG), labada dawo ayaa midba midka kale xoojiya.

Tijaabo Caafimaad

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NCT03574857	Jaamacadda Virginia	Wadne Failure\|Wadnaha oo Fashilmay oo Hoos u Dhaca Jajabka Wadnaha\|Wadnaha oo Aad u Xun	Juun 2018	Wajiga 4
NCT02546583	Jaamacadda Yale \| Machadka Wadnaha, Sambabka, iyo Dhiiga Qaranka (NHLBI)	Wadnaha oo Fashilmay	Ogosto 2015	Ma khuseyso
NCT02606253	Jaamacadda Vanderbilt \| Xarunta Caafimaadka ee Jaamacadda Vanderbilt	Wadnaha oo Fashilmay	Febraayo 2016	Wajiga 4
NCT00004360	Xarunta Qaranka ee Kheyraadka Cilmi-baarista (NCRR) \| Jaamacadda Waqooyi-galbeed \| Xafiiska Cudurrada Naadirka ah (ORD)	Sonkorowga Insipidus, Nephrogenic	Sebtembar 1995kii
NCT00000484	Machadka Qaranka ee Wadnaha, Sambabada, iyo Dhiiga (NHLBI)	Cudurada Wadnaha \|Cudurka Wadnaha \| Dhiigkarka	Abriil 1966kii	Wajiga 3